Because businesses vary in the types of services they offer and premises they occupy, many companies engage specialist cleaning contractors with experience and skill in a specific area of cleaning.

Commercial cleaners can focus in various areas such as factory cleaning, office cleaning and heavy-duty kitchen cleaning. Some of the areas these business cleaning services offer include forensic cleaning, toxic dust extraction and trauma scene cleaning. There are also specialist commercial cleaners that focus on environmentally sensitive cleaning services such as the removal of biodegradable material, chemicals and contaminated materials. Industrial cleaners specialising in the removal of toxic materials require certification and strict adherence to Health and Safety and industry regulations and legislation relating to the removal of hazardous materials.

Some commercial cleaners focus entirely on servicing a particular industry, such as the food services industry whereby the cleanliness of the premises must comply with industry implemented hygiene standards and pass routine council and government inspections. Often a business will engage a specialist cleaner on an as needed basis. These types of duties include window cleaning, yard cleaning or to assist following damages incurred from natural disasters or an ongoing issue. These kind of cleaning services include smoke and odour removal, water damage and pest control.